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Drug Repurposing Flubendazole to Suppress Tumorigenicity via PCSK9-dependent Inhibition and Potentiate Lenvatinib Therapy for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most lethal malignant cancers across the world. It has a poor prognosis and lacks effective therapies, especially for patients with advanced-stage cancer, indicating an urgent need for new therapies and novel therapeutic targets. Here, by screening the U....

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Detalles Bibliográficos
Autores principales: Jin, Wenjiao, Yu, Junming, Su, Yang, Lin, Hechun, Liu, Tengfei, Chen, Jing, Ge, Chao, Zhao, Fangyu, Geng, Qin, Mao, Lin, Jiang, Shuqing, Cui, Ying, Chen, Taoyang, Jiang, Guoping, Li, Jinjun, Miao, Chunxiao, Xiao, Xiuying, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158015/
https://www.ncbi.nlm.nih.gov/pubmed/37151886
http://dx.doi.org/10.7150/ijbs.81415