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Plasminogen Activator Inhibitor-1 Potentiates Neutrophil Infiltration and Tissue Injury in Colitis

The mechanism underlying inflammatory bowel disease (IBD) remains unclear. We aimed to identify early diagnostic biomarkers and understand their roles in the pathogenesis of IBD. Methods: We identified plasminogen activator inhibitor-1 (PAI-1) as a potential key gene that is upregulated in IBD based...

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Detalles Bibliográficos
Autores principales: Wang, Xinqiong, Guo, Li, Huang, Jiebin, Jiang, Shaowei, Li, Na, Mu, Hong-Hua, Xu, Chundi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158018/
https://www.ncbi.nlm.nih.gov/pubmed/37151884
http://dx.doi.org/10.7150/ijbs.75890