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Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer

Platinum drug-based chemotherapy plays a dominant role in OC (ovarian cancer) treatment. The expression of DNA damage repair (DDR) genes is critical in distinguishing drug-sensitive and drug-refractory patients, as well as in the development of drug resistance in long-term treated patients. CtBP is...

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Detalles Bibliográficos
Autores principales: Li, Jingjing, Wang, Yuan, Wang, Li, Hao, Dapeng, Li, Peipei, Su, Minxia, Zhao, Zhiqiang, Liu, Tianyu, Tai, Lixin, Lu, jinjian, Di, Li-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158025/
https://www.ncbi.nlm.nih.gov/pubmed/37151877
http://dx.doi.org/10.7150/ijbs.80952