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Exploration of spatial heterogeneity of tumor microenvironment in nasopharyngeal carcinoma via transcriptional digital spatial profiling

The heterogeneity of nasopharyngeal carcinoma (NPC) leads to mixed clinical outcomes. We collected 92 regions of interest from 41 biopsies of patients with untreated NPC and obtained their transcripts using GeoMx Digital Spatial Profiling (DSP) technology. Spatial heterogeneity was determined by mea...

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Detalles Bibliográficos
Autores principales: Wang, Liping, Wang, Dujuan, Zeng, Xiaojiao, Zhang, Qian, Wu, Huiqing, Liu, Jie, Wang, Yang, Liu, Guohong, Pan, Yunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158028/
https://www.ncbi.nlm.nih.gov/pubmed/37151882
http://dx.doi.org/10.7150/ijbs.74653