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Olfactomedin-4 deletion exacerbates DSS-induced colitis through a matrix metalloproteinase-9-dependent mechanism

Background and Aims: Olfactomedin-4 is a glycoprotein that is upregulated in inflamed gastrointestinal tissues. This study aimed to investigate the role and underlying mechanisms of olfactomedin-4 in ulcerative colitis. Methods: C57BL/6 mice and olfactomedin-4 knockout mice were fed dextran sulfate...

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Detalles Bibliográficos
Autores principales: Wang, Xinyu, Chen, Shenghui, Wang, Jinghua, Chen, Yishu, Guo, Yanjun, Wang, Qinqiu, Liu, Zhening, Zeng, Hang, Xu, Chengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158032/
https://www.ncbi.nlm.nih.gov/pubmed/37151883
http://dx.doi.org/10.7150/ijbs.80441