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Differentiated cultures of an immortalized human neural progenitor cell line do not replicate prions despite PrP(C) overexpression
Prions are misfolded proteins that accumulate within the brain in association with a rare group of fatal and infectious neurological disorders in humans and animals. A current challenge to research is a lack of in vitro model systems that are compatible with a wide range of prion strains, reproduce...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158546/ https://www.ncbi.nlm.nih.gov/pubmed/37131335 http://dx.doi.org/10.1080/19336896.2023.2206315 |