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Slit2/Robo1 signaling inhibits small‐cell lung cancer by targeting β‐catenin signaling in tumor cells and macrophages

Small‐cell lung cancer (SCLC) is an aggressive neuroendocrine subtype of lung cancer with poor patient prognosis. However, the mechanisms that regulate SCLC progression and metastasis remain undefined. Here, we show that the expression of the slit guidance ligand 2 (SLIT2) tumor suppressor gene is r...

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Detalles Bibliográficos
Autores principales: Ahirwar, Dinesh K., Peng, Bo, Charan, Manish, Misri, Swati, Mishra, Sanjay, Kaul, Kirti, Sassi, Salha, Gadepalli, Venkat Sundar, Siddiqui, Jalal, Miles, Wayne O., Ganju, Ramesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158774/
https://www.ncbi.nlm.nih.gov/pubmed/35838343
http://dx.doi.org/10.1002/1878-0261.13289