Cargando…

mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls

Mitochondrial DNA (mtDNA) somatic mutations play important roles in the initiation and progression of cancer. Although next‐generation sequencing (NGS) of paired tumor and control samples has become a common practice to identify tumor‐specific mtDNA mutations, the unique nature of mtDNA and NGS‐asso...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Wenjie, Liu, Yang, Su, Liping, Guo, Shanshan, Xie, Fanfan, Ji, Xiaoying, Zhou, Kaixiang, Guo, Xu, Gu, Xiwen, Xing, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158781/
https://www.ncbi.nlm.nih.gov/pubmed/36330809
http://dx.doi.org/10.1002/1878-0261.13335