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mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls
Mitochondrial DNA (mtDNA) somatic mutations play important roles in the initiation and progression of cancer. Although next‐generation sequencing (NGS) of paired tumor and control samples has become a common practice to identify tumor‐specific mtDNA mutations, the unique nature of mtDNA and NGS‐asso...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158781/ https://www.ncbi.nlm.nih.gov/pubmed/36330809 http://dx.doi.org/10.1002/1878-0261.13335 |