Cargando…

The trouble with triples: Examining the impact of measurement error in mediation analysis

Mediation analysis is used in genetic mapping studies to identify candidate gene mediators of quantitative trait loci (QTL). We consider genetic mediation analysis of triplets—sets of three variables consisting of a target trait, the genotype at a QTL for the target trait, and a candidate mediator t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gastonguay, Madeleine S, Keele, Gregory R, Churchill, Gary A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158839/
https://www.ncbi.nlm.nih.gov/pubmed/36932658
http://dx.doi.org/10.1093/genetics/iyad045