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The trouble with triples: Examining the impact of measurement error in mediation analysis
Mediation analysis is used in genetic mapping studies to identify candidate gene mediators of quantitative trait loci (QTL). We consider genetic mediation analysis of triplets—sets of three variables consisting of a target trait, the genotype at a QTL for the target trait, and a candidate mediator t...
Autores principales: | Gastonguay, Madeleine S, Keele, Gregory R, Churchill, Gary A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158839/ https://www.ncbi.nlm.nih.gov/pubmed/36932658 http://dx.doi.org/10.1093/genetics/iyad045 |
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