Impact of Clonal Architecture on Clinical Course and Prognosis in Patients With Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPNs) are caused by a somatic gain-of-function mutation in 1 of the 3 disease driver genes JAK2, MPL, or CALR. About half of the MPNs patients also carry additional somatic mutations that modify the clinical course. The order of acquisition of these gene mutations has b...

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Detalles Bibliográficos
Autores principales: Luque Paz, Damien, Bader, Michael S., Nienhold, Ronny, Rai, Shivam, Almeida Fonseca, Tiago, Stetka, Jan, Hao-Shen, Hui, Mild-Schneider, Gabriele, Passweg, Jakob R., Skoda, Radek C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158927/
https://www.ncbi.nlm.nih.gov/pubmed/37153874
http://dx.doi.org/10.1097/HS9.0000000000000885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158927/
https://www.ncbi.nlm.nih.gov/pubmed/37153874
http://dx.doi.org/10.1097/HS9.0000000000000885

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