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Screening for urinary markers predicting hematopoietic stem cell injury induced by busulfan using genetically diverse mice

BACKGROUND: Busulfan (BU) is an alkylating agent used as a conditioning agent prior to hematopoietic stem cell (HSC) transplantation as it is known to be cytotoxic to host hematopoietic stem and progenitor cells. The susceptibility of HSCs to BU injury plays an important role in the myeloablative ef...

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Detalles Bibliográficos
Autores principales: Sun, Yuhang, Guan, Bowen, Liu, Xing, Zhang, Lingyan, Wang, Xinpei, Meng, Aimin, Gao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158946/
https://www.ncbi.nlm.nih.gov/pubmed/37062934
http://dx.doi.org/10.1002/ame2.12320