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Spliceosome assembly and regulation: insights from analysis of highly reduced spliceosomes

Premessenger RNA splicing is catalyzed by the spliceosome, a multimegadalton RNA–protein complex that assembles in a highly regulated process on each intronic substrate. Most studies of splicing and spliceosomes have been carried out in human or S. cerevisiae model systems. There exists, however, a...

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Detalles Bibliográficos
Autores principales: Black, Corbin S., Whelan, Thomas A., Garside, Erin L., MacMillan, Andrew M., Fast, Naomi M., Rader, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158995/
https://www.ncbi.nlm.nih.gov/pubmed/36737103
http://dx.doi.org/10.1261/rna.079273.122