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Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus

BACKGROUND: Congenital Zika virus (ZIKV) infection can result in birth defects, including malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: African and Asian. Asian-lineage ZIKVs have been associated with adverse pregnancy outcomes in humans; howeve...

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Detalles Bibliográficos
Autores principales: Koenig, Michelle R., Mitzey, Ann M., Morgan, Terry K., Zeng, Xiankun, Simmons, Heather A., Mejia, Andres, Leyva Jaimes, Fernanda, Keding, Logan T., Crooks, Chelsea M., Weiler, Andrea M., Bohm, Ellie K., Aliota, Matthew T., Friedrich, Thomas C., Mohr, Emma L., Golos, Thaddeus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159132/
https://www.ncbi.nlm.nih.gov/pubmed/37141276
http://dx.doi.org/10.1371/journal.pone.0284964