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A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

Our understanding of how speed and persistence of cell migration affects the growth rate and size of tumors remains incomplete. To address this, we developed a mathematical model wherein cells migrate in two-dimensional space, divide, die or intravasate into the vasculature. Exploring a wide range o...

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Detalles Bibliográficos
Autores principales: Ghannoum, Salim, Fantini, Damiano, Zahoor, Muhammad, Reiterer, Veronika, Phuyal, Santosh, Leoncio Netto, Waldir, Sørensen, Øystein, Iyer, Arvind, Sengupta, Debarka, Prasmickaite, Lina, Mælandsmo, Gunhild Mari, Köhn-Luque, Alvaro, Farhan, Hesso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159355/
https://www.ncbi.nlm.nih.gov/pubmed/37068117
http://dx.doi.org/10.1371/journal.pcbi.1010995