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Targeting cellular respiration as a therapeutic strategy in glioblastoma

While glycolysis is abundant in malignancies, mitochondrial metabolism is significant as well. Mitochondria harbor the enzymes relevant for cellular respiration, which is a critical pathway for both regeneration of reduction equivalents and energy production in the form of ATP. The oxidation of NADH...

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Detalles Bibliográficos
Autores principales: Shang, Enyuan, Nguyen, Trang Thi Thu, Westhoff, Mike-Andrew, Karpel-Massler, Georg, Siegelin, Markus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159369/
https://www.ncbi.nlm.nih.gov/pubmed/37141415
http://dx.doi.org/10.18632/oncotarget.28424