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Roles for mycobacterial DinB2 in frameshift and substitution mutagenesis

Translesion synthesis by translesion polymerases is a conserved mechanism of DNA damage tolerance. In bacteria, DinB enzymes are the widely distributed promutagenic translesion polymerases. The role of DinBs in mycobacterial mutagenesis was unclear until recent studies revealed a role for mycobacter...

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Detalles Bibliográficos
Autores principales: Dupuy, Pierre, Ghosh, Shreya, Fay, Allison, Adefisayo, Oyindamola, Gupta, Richa, Shuman, Stewart, Glickman, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159617/
https://www.ncbi.nlm.nih.gov/pubmed/37141254
http://dx.doi.org/10.7554/eLife.83094