Impaired bone strength and bone microstructure in a novel early-onset osteoporotic rat model with a clinically relevant PLS3 mutation

Plastin 3 (PLS3), a protein involved in formation of filamentous actin (F-actin) bundles, is important in human bone health. Recent studies identify PLS3 as a novel bone regulator and PLS3 mutations can lead to a rare monogenic early-onset osteoporosis. However, the mechanism of PLS3 mutation leadin...

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Detalles Bibliográficos
Autores principales: Hu, Jing, Zhou, Bingna, Lin, Xiaoyun, Zhang, Qian, Guan, Feifei, Sun, Lei, Liu, Jiayi, Wang, Ou, Jiang, Yan, Xia, Wei-bo, Xing, Xiaoping, Li, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159618/
https://www.ncbi.nlm.nih.gov/pubmed/37083757
http://dx.doi.org/10.7554/eLife.80365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159618/
https://www.ncbi.nlm.nih.gov/pubmed/37083757
http://dx.doi.org/10.7554/eLife.80365

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