A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice

Fatty acid amide hydrolase (FAAH) degrades the endocannabinoid anandamide. A polymorphism in FAAH (FAAH C385A) reduces FAAH expression, increases anandamide levels, and increases the risk of obesity. Nevertheless, some studies have found no association between FAAH C385A and obesity. We investigated...

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Detalles Bibliográficos
Autores principales: Balsevich, Georgia, Petrie, Gavin N, Heinz, Daniel E, Singh, Arashdeep, Aukema, Robert J, Hunker, Avery C, Vecchiarelli, Haley A, Yau, Hiulan, Sticht, Martin, Thompson, Roger J, Lee, Francis S, Zweifel, Larry S, Chelikani, Prasanth K, Gassen, Nils C, Hill, Matthew N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159625/
https://www.ncbi.nlm.nih.gov/pubmed/37039453
http://dx.doi.org/10.7554/eLife.81919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159625/
https://www.ncbi.nlm.nih.gov/pubmed/37039453
http://dx.doi.org/10.7554/eLife.81919

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