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Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-1
BACKGROUND & AIMS: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly heterozygous, which allows the co-expression of wild-t...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159820/ https://www.ncbi.nlm.nih.gov/pubmed/37153687 http://dx.doi.org/10.1016/j.jhepr.2023.100691 |