Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-1

BACKGROUND & AIMS: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly heterozygous, which allows the co-expression of wild-t...

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Detalles Bibliográficos
Autores principales: Gest, Caroline, Sena, Sandra, Dif, Lydia, Neaud, Véronique, Loesch, Robin, Dugot-Senant, Nathalie, Paysan, Lisa, Piquet, Léo, Robbe, Terezinha, Allain, Nathalie, Dembele, Doulaye, Guettier, Catherine, Bioulac-Sage, Paulette, Rullier, Anne, Le Bail, Brigitte, Grosset, Christophe F., Saltel, Frédéric, Lagrée, Valérie, Colnot, Sabine, Moreau, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159820/
https://www.ncbi.nlm.nih.gov/pubmed/37153687
http://dx.doi.org/10.1016/j.jhepr.2023.100691

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