Targeting bromodomain-containing proteins: research advances of drug discovery

Bromodomain (BD) is an evolutionarily conserved protein module found in 46 different BD-containing proteins (BCPs). BD acts as a specific reader for acetylated lysine residues (KAc) and serves an essential role in transcriptional regulation, chromatin remodeling, DNA damage repair, and cell prolifer...

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Detalles Bibliográficos
Autores principales: Pan, Zhaoping, Zhao, Yuxi, Wang, Xiaoyun, Xie, Xin, Liu, Mingxia, Zhang, Kaiyao, Wang, Lian, Bai, Ding, Foster, Leonard J., Shu, Rui, He, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159834/
https://www.ncbi.nlm.nih.gov/pubmed/37142850
http://dx.doi.org/10.1186/s43556-023-00127-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159834/
https://www.ncbi.nlm.nih.gov/pubmed/37142850
http://dx.doi.org/10.1186/s43556-023-00127-1

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