Cargando…

ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages

Autophagy is a cellular innate-immune defence mechanism against intracellular microorganisms, including Mycobacterium tuberculosis (Mtb). How canonical and non-canonical autophagy function to control Mtb infection in phagosomes and the cytosol remains unresolved. Macrophages are the main host cell i...

Descripción completa

Detalles Bibliográficos
Autores principales: Aylan, Beren, Bernard, Elliott M., Pellegrino, Enrica, Botella, Laure, Fearns, Antony, Athanasiadi, Natalia, Bussi, Claudio, Santucci, Pierre, Gutierrez, Maximiliano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159855/
https://www.ncbi.nlm.nih.gov/pubmed/36959508
http://dx.doi.org/10.1038/s41564-023-01335-9