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ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages
Autophagy is a cellular innate-immune defence mechanism against intracellular microorganisms, including Mycobacterium tuberculosis (Mtb). How canonical and non-canonical autophagy function to control Mtb infection in phagosomes and the cytosol remains unresolved. Macrophages are the main host cell i...
Autores principales: | Aylan, Beren, Bernard, Elliott M., Pellegrino, Enrica, Botella, Laure, Fearns, Antony, Athanasiadi, Natalia, Bussi, Claudio, Santucci, Pierre, Gutierrez, Maximiliano G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159855/ https://www.ncbi.nlm.nih.gov/pubmed/36959508 http://dx.doi.org/10.1038/s41564-023-01335-9 |
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