Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products

BACKGROUND AIMS: Chimeric antigen receptor (CAR) T cells have demonstrated remarkable efficacy against hematological malignancies; however, they have not experienced the same success against solid tumors such as glioblastoma (GBM). There is a growing need for high-throughput functional screening pla...

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Detalles Bibliográficos
Autores principales: Logun, Meghan, Colonna, Maxwell B., Mueller, Katherine P., Ventarapragada, Divya, Rodier, Riley, Tondepu, Chaitanya, Piscopo, Nicole J., Das, Amritava, Chvatal, Stacie, Hayes, Heather B., Capitini, Christian M., Brat, Daniel J., Kotanchek, Theresa, Edison, Arthur S., Saha, Krishanu, Karumbaiah, Lohitash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159906/
https://www.ncbi.nlm.nih.gov/pubmed/36849306
http://dx.doi.org/10.1016/j.jcyt.2023.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159906/
https://www.ncbi.nlm.nih.gov/pubmed/36849306
http://dx.doi.org/10.1016/j.jcyt.2023.01.008

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