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Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products
BACKGROUND AIMS: Chimeric antigen receptor (CAR) T cells have demonstrated remarkable efficacy against hematological malignancies; however, they have not experienced the same success against solid tumors such as glioblastoma (GBM). There is a growing need for high-throughput functional screening pla...
Autores principales: | Logun, Meghan, Colonna, Maxwell B., Mueller, Katherine P., Ventarapragada, Divya, Rodier, Riley, Tondepu, Chaitanya, Piscopo, Nicole J., Das, Amritava, Chvatal, Stacie, Hayes, Heather B., Capitini, Christian M., Brat, Daniel J., Kotanchek, Theresa, Edison, Arthur S., Saha, Krishanu, Karumbaiah, Lohitash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159906/ https://www.ncbi.nlm.nih.gov/pubmed/36849306 http://dx.doi.org/10.1016/j.jcyt.2023.01.008 |
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