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CHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer

Current treatment options for prostate cancer focus on targeting androgen receptor (AR) signaling. Inhibiting effects of AR may activate neuroendocrine differentiation and lineage plasticity pathways, thereby promoting the development of neuroendocrine prostate cancer (NEPC). Understanding the regul...

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Detalles Bibliográficos
Autores principales: Wen, Yu-Ching, Tram, Van Thi Ngoc, Chen, Wei-Hao, Li, Chien-Hsiu, Yeh, Hsiu-Lien, Thuy Dung, Phan Vu, Jiang, Kuo-Ching, Li, Han-Ru, Huang, Jiaoti, Hsiao, Michael, Chen, Wei-Yu, Liu, Yen-Nien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160040/
https://www.ncbi.nlm.nih.gov/pubmed/37142586
http://dx.doi.org/10.1038/s41419-023-05836-7