Cargando…

CHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer

Current treatment options for prostate cancer focus on targeting androgen receptor (AR) signaling. Inhibiting effects of AR may activate neuroendocrine differentiation and lineage plasticity pathways, thereby promoting the development of neuroendocrine prostate cancer (NEPC). Understanding the regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Yu-Ching, Tram, Van Thi Ngoc, Chen, Wei-Hao, Li, Chien-Hsiu, Yeh, Hsiu-Lien, Thuy Dung, Phan Vu, Jiang, Kuo-Ching, Li, Han-Ru, Huang, Jiaoti, Hsiao, Michael, Chen, Wei-Yu, Liu, Yen-Nien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160040/ https://www.ncbi.nlm.nih.gov/pubmed/37142586 http://dx.doi.org/10.1038/s41419-023-05836-7

Ejemplares similares

Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance
por: Chen, Wei-Yu, et al.
Publicado: (2021)

Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency
por: Wen, Yu-Ching, et al.
Publicado: (2022)

TCF7L1 regulates cytokine response and neuroendocrine differentiation of prostate cancer
por: Wen, Yu-Ching, et al.
Publicado: (2021)

Polymorphisms in the Cholinergic Receptors Muscarinic (CHRM2 and CHRM3) Genes and Alzheimer’s Disease
por: Chee, Lim Ya, et al.
Publicado: (2018)

Pancreas-specific CHRM3 activation causes pancreatitis in mice
por: Wan, Jianhua, et al.
Publicado: (2021)

Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances
por: Sanfilippo, Cristina, et al.
Publicado: (2023)

Reciprocal Induction of MDM2 and MYCN in Neural and Neuroendocrine Cancers
por: Tran, Hung N., et al.
Publicado: (2020)

The Functional Haplotypes of CHRM3 Modulate mRNA Expression and Associate with Bladder Cancer among a Chinese Han Population in Kaohsiung City
por: Wang, Chiang-Ting, et al.
Publicado: (2016)

Evaluation of Dietary Intake in Individuals with Mild Cognitive Impairment
por: Nien, Shih-Wei, et al.
Publicado: (2023)

Dysbindin Domain-Containing 1 in Prostate Cancer: New Insights into Bioinformatic Validation of Molecular and Immunological Features
por: Tram, Van Thi Ngoc, et al.
Publicado: (2023)

Interplay of Epidermal Growth Factor Receptor and Signal Transducer and Activator of Transcription 3 in Prostate Cancer: Beyond Androgen Receptor Transactivation
por: Lin, Shian-Ren, et al.
Publicado: (2021)

Network toxicology and molecular docking analyses on strychnine indicate CHRM1 is a potential neurotoxic target
por: Dai, Jialin, et al.
Publicado: (2022)

A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans
por: Cheng, Zhongshan, et al.
Publicado: (2019)

A homozygous missense variant in CHRM3 associated with familial urinary bladder disease
por: Beaman, Glenda M., et al.
Publicado: (2019)

MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma
por: Floros, Konstantinos V., et al.
Publicado: (2022)

Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway
por: Yeh, Yen-Hsiu, et al.
Publicado: (2018)

Androgen receptor regulates SRC expression through microRNA-203
por: Siu, Man Kit, et al.
Publicado: (2016)

Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands
por: Wang, Yiyu, et al.
Publicado: (2022)

The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer
por: Ji, Yiyi, et al.
Publicado: (2023)

Point-of-care ultrasound in Management for Dyspneic Uremic Patients: a case report
por: Wang, Pei-Hsiu, et al.
Publicado: (2019)

Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
por: Tsai, Yuan-Chin, et al.
Publicado: (2018)

Weak up-regulation of serum response factor in gastric ulcers in patients with co-morbidities is associated with increased risk of recurrent bleeding
por: Cheng, Hsiu-Chi, et al.
Publicado: (2011)

The new SRS/FSRT technique HyperArc for benign brain lesions: a dosimetric analysis
por: Ho, Hsiu-Wen, et al.
Publicado: (2021)

SMAD9-MYCN positive feedback loop represents a unique dependency for MYCN-amplified neuroblastoma
por: Tan, Kezhe, et al.
Publicado: (2022)

Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma
por: Seier, Johanna A, et al.
Publicado: (2021)

MYCN and the epigenome
por: He, Stanley, et al.
Publicado: (2013)

CHRM3 is a novel prognostic factor of poor prognosis and promotes glioblastoma progression via activation of oncogenic invasive growth factors
por: ZHANG, BIN, et al.
Publicado: (2023)

Implementation of the plasma MYCN/NAGK ratio to detect MYCN amplification in patients with neuroblastoma
por: Su, Yan, et al.
Publicado: (2020)

Antrodia cinnamomea Suppress Dengue Virus Infection through Enhancing the Secretion of Interferon-Alpha
por: Chen, Yi-Ju, et al.
Publicado: (2022)

Neuroendocrine cells of the prostate: Histology, biological functions, and molecular mechanisms
por: Butler, William, et al.
Publicado: (2021)

MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma
por: Agarwal, Saurabh, et al.
Publicado: (2018)

An app for predicting nurse intention to quit the job using artificial neural networks (ANNs) in Microsoft Excel
por: Chen, Hsiu-Chin, et al.
Publicado: (2022)

Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate
por: Lien, Hsiu-Man, et al.
Publicado: (2011)

MYCN is amplified during S phase, and c-myb is involved in controlling MYCN expression and amplification in MYCN-amplified neuroblastoma cell lines
por: Aygun, Nevim, et al.
Publicado: (2019)

The outcomes of right-sided and left-sided colonic diverticulitis following non-operative management: a systematic review and meta-analysis
por: Huang, Sih-Shiang, et al.
Publicado: (2022)

MYCN mRNA degradation and cancer suppression by a selective small-molecule inhibitor in MYCN-amplified neuroblastoma
por: Liu, Tao, et al.
Publicado: (2022)

Correction: MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma
por: Agarwal, Saurabh, et al.
Publicado: (2018)

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer
por: Chen, Wei-Yu, et al.
Publicado: (2014)

Prognostic factors and population-based analysis of melanoma with sentinel lymph node biopsy
por: Wu, Ping-Chung, et al.
Publicado: (2021)

MicroRNA-30e inhibits adhesion, migration, invasion and cell cycle progression of prostate cancer cells via inhibition of the activation of the MAPK signaling pathway by downregulating CHRM3
por: Zheng, Xin-Min, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h0520i4h7msu5t8l7nhjqgnf7p