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Large scale sequence alignment via efficient inference in generative models

Finding alignments between millions of reads and genome sequences is crucial in computational biology. Since the standard alignment algorithm has a large computational cost, heuristics have been developed to speed up this task. Though orders of magnitude faster, these methods lack theoretical guaran...

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Detalles Bibliográficos
Autores principales: Mongia, Mihir, Shen, Chengze, Davoodi, Arash Gholami, Marçais, Guillaume, Mohimani, Hosein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160065/
https://www.ncbi.nlm.nih.gov/pubmed/37142645
http://dx.doi.org/10.1038/s41598-023-34257-x