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Intratumor heterogeneity and cell secretome promote chemotherapy resistance and progression of colorectal cancer

The major underlying cause for the high mortality rate in colorectal cancer (CRC) relies on its drug resistance, to which intratumor heterogeneity (ITH) contributes substantially. CRC tumors have been reported to comprise heterogeneous populations of cancer cells that can be grouped into 4 consensus...

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Detalles Bibliográficos
Autores principales: Källberg, Julia, Harrison, Alexandra, March, Valerie, Bērziņa, Santa, Nemazanyy, Ivan, Kepp, Oliver, Kroemer, Guido, Mouillet-Richard, Sophie, Laurent-Puig, Pierre, Taly, Valérie, Xiao, Wenjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160076/
https://www.ncbi.nlm.nih.gov/pubmed/37142595
http://dx.doi.org/10.1038/s41419-023-05806-z