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Intratumor heterogeneity and cell secretome promote chemotherapy resistance and progression of colorectal cancer
The major underlying cause for the high mortality rate in colorectal cancer (CRC) relies on its drug resistance, to which intratumor heterogeneity (ITH) contributes substantially. CRC tumors have been reported to comprise heterogeneous populations of cancer cells that can be grouped into 4 consensus...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160076/ https://www.ncbi.nlm.nih.gov/pubmed/37142595 http://dx.doi.org/10.1038/s41419-023-05806-z |