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Antiproliferative effects of mitochondria-targeted N-acetylcysteine and analogs in cancer cells

N-acetylcysteine (NAC) has been used as an antioxidant drug in tumor cells and preclinical mice tumor xenografts, and it improves adaptive immunotherapy in melanoma. NAC is not readily bioavailable and is used in high concentrations. The effects of NAC have been attributed to its antioxidant and red...

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Detalles Bibliográficos
Autores principales: Cheng, Gang, Hardy, Micael, Kalyanaraman, Balaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160116/
https://www.ncbi.nlm.nih.gov/pubmed/37142668
http://dx.doi.org/10.1038/s41598-023-34266-w