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Transcriptomic Profiling Reveals Discrete Poststroke Dementia Neuronal and Gliovascular Signatures

Poststroke dementia (PSD) is associated with pathology in frontal brain regions, in particular dorsolateral prefrontal cortex (DLPFC) neurons and white matter, remote from the infarct. We hypothesised that PSD results from progressive DLPFC neuronal damage, associated with frontal white matter gliov...

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Detalles Bibliográficos
Autores principales: Waller, Rachel, Hase, Yoshiki, Simpson, Julie E., Heath, Paul R., Wyles, Matthew, Kalaria, Rajesh N., Wharton, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160172/
https://www.ncbi.nlm.nih.gov/pubmed/35639336
http://dx.doi.org/10.1007/s12975-022-01038-z