Metformin promotes osteogenic differentiation and prevents hyperglycaemia-induced osteoporosis by suppressing PPARγ expression: Metformin prevents osteoporosis by suppressing PPARγ

Metformin can prevent hyperglycaemia-induced osteoporosis and decrease the bone fracture rate, but the mechanism has not been fully elucidated. To reveal the mechanism by which metformin affects hyperglycaemia-induced osteoporosis, we treat a mouse osteoporosis cell model with metformin and find tha...

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Detalles Bibliográficos
Autores principales: Zheng, Lifeng, Shen, Ximei, Xie, Yun, Lian, Hong, Yan, Sunjie, Wang, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160221/
https://www.ncbi.nlm.nih.gov/pubmed/36951483
http://dx.doi.org/10.3724/abbs.2023043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160221/
https://www.ncbi.nlm.nih.gov/pubmed/36951483
http://dx.doi.org/10.3724/abbs.2023043

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