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Upregulation of DRG protein TMEM100 facilitates dryskin-induced pruritus by enhancing TRPA1 channel function: Upregulation of TMEM100 facilitates dry skin-induced pruritus

The dry skin tortures numerous patients with severe itch. The transient receptor potential cation channel V member 1 (TRPV1) and A member 1 (TRPA1) are two essential receptors for peripheral neural coding of itch sensory, mediating histaminergic and nonhistaminergic itch separately. In the dorsal ro...

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Detalles Bibliográficos
Autores principales: Pan, Chao, Jiao, Yingfu, Kong, Dexu, Deng, Haoyue, Xu, Saihong, Tang, Dan, Yin, Wen, Gao, Po, Yu, Weifeng, Fan, Yinghui, Wen, Daxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160222/
https://www.ncbi.nlm.nih.gov/pubmed/36514220
http://dx.doi.org/10.3724/abbs.2022180