PRIMPOL competes with RAD51 to resolve G-quadruplex-induced replication stress via its interaction with RPA: PRIMPOL resolves G4-induced replication stress

PRIMPOL (primase-polymerase) is a recently discovered DNA primase-polymerase involved in DNA damage tolerance and replication stress response in eukaryotic cells. However, the detailed mechanism of the PRIMPOL response to replication stress remains elusive. Here, we demonstrate that replication-rela...

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Detalles Bibliográficos
Autores principales: Li, Tingfang, Tang, Lu, Kou, Haomeng, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160237/
https://www.ncbi.nlm.nih.gov/pubmed/36647718
http://dx.doi.org/10.3724/abbs.2022165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160237/
https://www.ncbi.nlm.nih.gov/pubmed/36647718
http://dx.doi.org/10.3724/abbs.2022165

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