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Dasatinib targets c-Src kinase in cardiotoxicity

Dasatinib is a multitargeted kinase inhibitor used for treatment of chronic myeloid leukemia and acute lymphoblastic leukemia. Unfortunately, treatment of cancer patients with some kinase inhibitors has been associated with cardiotoxicity. Cancer treatment with dasatinib has been reported to be asso...

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Detalles Bibliográficos
Autores principales: Elmadani, Manar, Raatikainen, Sami, Mattila, Orvokki, Alakoski, Tarja, Piuhola, Jarkko, Åström, Pirjo, Tenhunen, Olli, Magga, Johanna, Kerkelä, Risto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160240/
https://www.ncbi.nlm.nih.gov/pubmed/37152411
http://dx.doi.org/10.1016/j.toxrep.2023.04.013