Amlodipine rescues advanced iron overload cardiomyopathy in hemojuvelin knockout murine model: Clinical implications

BACKGROUND: Iron overload cardiomyopathy (IOC) is a major co-morbidity of genetic hemochromatosis and secondary iron overload with limited therapeutic options. We aim to investigate mechanisms of rescue action of amlodipine in the murine model of iron overload, characterize changes in human cardiac...

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Detalles Bibliográficos
Autores principales: Zhabyeyev, Pavel, Sadasivan, Chandu, Shah, Saumya, Wang, Faqi, Oudit, Gavin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160373/
https://www.ncbi.nlm.nih.gov/pubmed/37153462
http://dx.doi.org/10.3389/fcvm.2023.1129349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160373/
https://www.ncbi.nlm.nih.gov/pubmed/37153462
http://dx.doi.org/10.3389/fcvm.2023.1129349

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