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Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function

The HRAS gene plays a crucial role in regulating essential cellular processes for life, and this gene's misregulation is linked to the development of various types of cancers. Nonsynonymous single nucleotide polymorphisms (nsSNPs) within the coding region of HRAS can cause detrimental mutations...

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Detalles Bibliográficos
Autores principales: Ali, Sadaqat, Ali, Usman, Qamar, Adeem, Zafar, Imran, Yaqoob, Muhammad, Ain, Qurat ul, Rashid, Summya, Sharma, Rohit, Nafidi, Hiba-Allah, Bin Jardan, Yousef A., Bourhia, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160440/
https://www.ncbi.nlm.nih.gov/pubmed/37153521
http://dx.doi.org/10.3389/fchem.2023.1173624