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Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function
The HRAS gene plays a crucial role in regulating essential cellular processes for life, and this gene's misregulation is linked to the development of various types of cancers. Nonsynonymous single nucleotide polymorphisms (nsSNPs) within the coding region of HRAS can cause detrimental mutations...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160440/ https://www.ncbi.nlm.nih.gov/pubmed/37153521 http://dx.doi.org/10.3389/fchem.2023.1173624 |