Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity

INTRODUCTION: Asthma is characterized by an imbalance between proteases and their inhibitors. Hence, an attractive therapeutic option could be to interfere with asthma-associated proteases. Here we exploited this option by assessing the impact of nafamostat, a serine protease inhibitor known to neut...

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Detalles Bibliográficos
Autores principales: Allam, Venkata Sita Rama Raju, Waern, Ida, Taha, Sowsan, Akula, Srinivas, Wernersson, Sara, Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160450/
https://www.ncbi.nlm.nih.gov/pubmed/37153590
http://dx.doi.org/10.3389/fimmu.2023.1136780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160450/
https://www.ncbi.nlm.nih.gov/pubmed/37153590
http://dx.doi.org/10.3389/fimmu.2023.1136780

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