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Biological evaluation and in silico studies of novel compounds as potent TAAR1 agonists that could be used in schizophrenia treatment

Introduction: Schizophrenia is a serious mental illness that requires effective treatment with minimal adverse effects. As preclinical and clinical research progresses, trace amine-associated receptor 1 (TAAR1) is becoming a potential new target for the treatment of schizophrenia. Methods: We used m...

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Detalles Bibliográficos
Autores principales: Wang, Yunjie, Liu, Zhaofeng, Lu, Jing, Wang, Wenyan, Wang, Lin, Yang, Yifei, Wang, Hongbo, Ye, Liang, Zhang, Jianzhao, Tian, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160475/
https://www.ncbi.nlm.nih.gov/pubmed/37153799
http://dx.doi.org/10.3389/fphar.2023.1161964