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Type 2 deiodinase is expressed in anaplastic thyroid carcinoma and its inhibition causes cell senescence

Anaplastic thyroid cancer (ATC) is a rare thyroid tumor that frequently originates from the dedifferentiation of a well-differentiated papillary or follicular thyroid cancer. Type 2 deiodinase (D2), responsible for the activation of the thyroid hormone thyroxine into tri-iodothyronine (T(3)), is exp...

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Detalles Bibliográficos
Autores principales: Angela De Stefano, Maria, Porcelli, Tommaso, Ambrosio, Raffaele, Luongo, Cristina, Raia, Maddalena, Schlumberger, Martin, Salvatore, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160549/
https://www.ncbi.nlm.nih.gov/pubmed/36877008
http://dx.doi.org/10.1530/ERC-23-0016