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Type 2 deiodinase is expressed in anaplastic thyroid carcinoma and its inhibition causes cell senescence
Anaplastic thyroid cancer (ATC) is a rare thyroid tumor that frequently originates from the dedifferentiation of a well-differentiated papillary or follicular thyroid cancer. Type 2 deiodinase (D2), responsible for the activation of the thyroid hormone thyroxine into tri-iodothyronine (T(3)), is exp...
Autores principales: | Angela De Stefano, Maria, Porcelli, Tommaso, Ambrosio, Raffaele, Luongo, Cristina, Raia, Maddalena, Schlumberger, Martin, Salvatore, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160549/ https://www.ncbi.nlm.nih.gov/pubmed/36877008 http://dx.doi.org/10.1530/ERC-23-0016 |
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