Biological injection therapy with leukocyte-poor platelet-rich plasma induces cellular alterations, enhancement of lubricin, and inflammatory downregulation in vivo in human knees: A controlled, prospective human clinical trial based on mass spectrometry imaging analysis

OBJECTIVE: To investigate the in vivo biological effects of leukocyte-poor platelet-rich plasma (LpPRP) treatment in human synovial layer to establish the cellular basis for a prolonged clinical improvement. METHODS: Synovial tissues (n = 367) were prospectively collected from patients undergoing ar...

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Detalles Bibliográficos
Autores principales: Baltzer, Axel W., Casadonte, Rita, Korff, Alexei, Baltzer, Lea Merline, Kriegsmann, Katharina, Kriegsmann, Mark, Kriegsmann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160617/
https://www.ncbi.nlm.nih.gov/pubmed/37151865
http://dx.doi.org/10.3389/fsurg.2023.1169112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160617/
https://www.ncbi.nlm.nih.gov/pubmed/37151865
http://dx.doi.org/10.3389/fsurg.2023.1169112

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