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Persistent T cell proliferation and MDSCs expansion precede incomplete CD4(+) T cell recovery in people with acute HIV-1 infection with early ART
HIV-1 infection causes T cell dysfunction that cannot be fully restored by anti-retroviral therapy (ART). Myeloid-derived suppressor cells (MDSCs) expand and suppress T cell function during viral infection. In this study, we evaluated the dynamics of phenotypes and function of T cells and MDSCs and...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160758/ https://www.ncbi.nlm.nih.gov/pubmed/37153387 http://dx.doi.org/10.1016/j.heliyon.2023.e15590 |