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Persistent T cell proliferation and MDSCs expansion precede incomplete CD4(+) T cell recovery in people with acute HIV-1 infection with early ART

HIV-1 infection causes T cell dysfunction that cannot be fully restored by anti-retroviral therapy (ART). Myeloid-derived suppressor cells (MDSCs) expand and suppress T cell function during viral infection. In this study, we evaluated the dynamics of phenotypes and function of T cells and MDSCs and...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Yan, Ping, Wang, Rui, Lu, Xiaofan, Zhang, Yang, Su, Bin, Zhang, Xin, Yuan, Lin, Liu, Zhiying, Jiang, Wei, Zhang, Tong, Wu, Hao, Huang, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160758/
https://www.ncbi.nlm.nih.gov/pubmed/37153387
http://dx.doi.org/10.1016/j.heliyon.2023.e15590