SRC2 controls CD4(+) T cell activation via stimulating c-Myc-mediated upregulation of amino acid transporter Slc7a5

T cell activation stimulates substantially increased protein synthesis activity to accumulate sufficient biomass for cell proliferation. The protein synthesis is fueled by the amino acids transported from the environment. Steroid nuclear receptor coactivator 2 (SRC2) is a member of a family of trans...

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Detalles Bibliográficos
Autores principales: Zhang, Wencan, Cao, Xu, Zhong, Xiancai, Wu, Hongmin, Shi, Yun, Feng, Mingye, Wang, Yi-Chang, Ann, David, Gwack, Yousang, Yuan, Yate-Ching, Shang, Weirong, Sun, Zuoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160970/
https://www.ncbi.nlm.nih.gov/pubmed/37094160
http://dx.doi.org/10.1073/pnas.2221352120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160970/
https://www.ncbi.nlm.nih.gov/pubmed/37094160
http://dx.doi.org/10.1073/pnas.2221352120

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