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SRC2 controls CD4(+) T cell activation via stimulating c-Myc-mediated upregulation of amino acid transporter Slc7a5
T cell activation stimulates substantially increased protein synthesis activity to accumulate sufficient biomass for cell proliferation. The protein synthesis is fueled by the amino acids transported from the environment. Steroid nuclear receptor coactivator 2 (SRC2) is a member of a family of trans...
Autores principales: | Zhang, Wencan, Cao, Xu, Zhong, Xiancai, Wu, Hongmin, Shi, Yun, Feng, Mingye, Wang, Yi-Chang, Ann, David, Gwack, Yousang, Yuan, Yate-Ching, Shang, Weirong, Sun, Zuoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160970/ https://www.ncbi.nlm.nih.gov/pubmed/37094160 http://dx.doi.org/10.1073/pnas.2221352120 |
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