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Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM
The HIV-1 capsid houses the viral genome and interacts extensively with host cell proteins throughout the viral life cycle. It is composed of capsid protein (CA), which assembles into a conical fullerene lattice composed of roughly 200 CA hexamers and 12 CA pentamers. Previous structural analyses of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160977/ https://www.ncbi.nlm.nih.gov/pubmed/37094124 http://dx.doi.org/10.1073/pnas.2220545120 |