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Exploiting conformational dynamics to modulate the function of designed proteins
With the recent success in calculating protein structures from amino acid sequences using artificial intelligence-based algorithms, an important next step is to decipher how dynamics is encoded by the primary protein sequence so as to better predict function. Such dynamics information is critical fo...
Autores principales: | Rennella, Enrico, Sahtoe, Danny D., Baker, David, Kay, Lewis E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161014/ https://www.ncbi.nlm.nih.gov/pubmed/37094170 http://dx.doi.org/10.1073/pnas.2303149120 |
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