Polyphotosensitizer‐Based Nanoparticles with Michael Addition Acceptors Inhibiting GST Activity and Cisplatin Deactivation for Enhanced Chemotherapy and Photodynamic Immunotherapy

Glutathione S‐transferase (GST), which is a key enzyme in the conjugation reaction of glutathione (GSH), is overexpressed in cancer cells, leading to cisplatin deactivation and ultimately drug resistance. In addition, many tumors are immune “cold tumors,” limiting the application of immune checkpoin...

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Detalles Bibliográficos
Autores principales: Zhao, Qinxin, Liang, Ganghao, Guo, Boda, Wang, Wenkuan, Yang, Chao, Chen, Dong, Yang, Feiya, Xiao, Haihua, Xing, Nianzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161037/
https://www.ncbi.nlm.nih.gov/pubmed/36930173
http://dx.doi.org/10.1002/advs.202300175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161037/
https://www.ncbi.nlm.nih.gov/pubmed/36930173
http://dx.doi.org/10.1002/advs.202300175

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