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Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage

CRISPR-Cas systems are widespread adaptive antiviral systems used in prokaryotes. Some phages, in turn, although have small genomes can economize the use of genetic space to encode compact or incomplete CRISPR-Cas systems to inhibit the host and establish infection. Phage ICP1, infecting Vibrio chol...

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Detalles Bibliográficos
Autores principales: Zhang, Manling, Peng, Ruchao, Peng, Qi, Liu, Sheng, Li, Zhiteng, Zhang, Yuqin, Song, Hao, Yang, Jia, Xing, Xiao, Wang, Peiyi, Qi, Jianxun, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161043/
https://www.ncbi.nlm.nih.gov/pubmed/37094126
http://dx.doi.org/10.1073/pnas.2215098120